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The 10 Best Anti-Aging Serums to Use Right Now, According to Experts

Fine lines and wrinkles beware.

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best anti-aging serums
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Figuring out the best way to battle the signs of aging can be a seriously expensive and time-consuming task. To demystify the anti-aging process, we sat down with board-certified and nationally-acclaimed dermatologic surgeon Dr. Dendy Engelman and award-winning esthetician Jeannel Astarita, owner of Just Ageless, for their expert take on all things anti-aging serums.

What to Know About Anti-Aging Serums

Both Engelman and Astarita agree that antioxidants, retinols, and hyaluronic acid are some of the key ingredients to look for when selecting an anti-aging serum. “It’s important to look for products that don’t just make claims about reducing the appearance of fine lines,” Astarita said. “You want products that contain ingredients that really help support skin health. Healthy skin will look and behave like younger skin.”

Selection of anti-aging serums is key, but there are also some other factors that can make these products even more effective in helping to correct lines, wrinkles, sun damage, and uneven texture. Dr. Engelman and Astarita both agree that skincare products should be layered thinnest to thickest.

“A good rule of thumb is to start with the lightest product and finish with the thickest, allowing each layer to be fully absorbed by the skin,” Dr. Engelman explained. “A serum placed on top of a moisturizer will not allow the serum to be fully absorbed since the smaller molecules cannot penetrate the larger ones.”

Dr. Engelman also encourages the use of at-home devices like microneedling rollers and toning devices to allow maximum absorption of your anti-aging serums.

The Best Anti-Aging Serums

How We Chose

If you want professional results, you should always start with an actual professional. That's exactly what we did: We decided to tap our go-to skincare experts for their thoughts on the best serums you can implement into your routine. The following products were either hand-selected by Dr. Engelman, Astarita, or by us with the guidance of our experts' tips.

1
Best Collagen Booster

The INKEY List The INKEY List Collagen Booster Firming Peptide Serum

The INKEY List Collagen Booster Firming Peptide Serum
1
Best Collagen Booster

The INKEY List The INKEY List Collagen Booster Firming Peptide Serum

$11 at Sephora$16 at Amazon

Astarita notes that peptides are "messenger cells" that communicate with your skin cells to diminish the production of excess pigment or to speed cell turnover, which makes them an essential part of any anti-aging skincare routine. 

This lightweight serum from The INKEY List does just that while boosting collagen production and firming up the skin.

More: The Best Vitamin C Serums Worth Using Every Day

2
Quick Results

iS CLINICAL iS CLINICAL Active Serum

iS CLINICAL Active Serum
2
Quick Results

iS CLINICAL iS CLINICAL Active Serum

If you want your skin to improve overnight, this is the bottle to reach for. Many products provide results over time, but we saw a substantial improvement in skin texture and tone after just one use. It's great for anti-aging as well as fighting acne for a clear complexion overall.

3
Fan-Favorite

SkinCeuticals SkinCeuticals C E Ferulic Serum

SkinCeuticals C E Ferulic Serum
3
Fan-Favorite

SkinCeuticals SkinCeuticals C E Ferulic Serum

This serum is a tried-and-true favorite of both our editors and our experts for its powerful blend of antioxidants that work together to significantly improve fine lines and wrinkles. 

Dr. Engelman also notes that this serum also helps neutralize free-radical damage and reverses environmental aging, and calls this serum the “gold standard” of topical antioxidants.

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4
Best for Dark Spots

Caudalie Caudalie Vinoperfect Anti Dark Spot Serum

Caudalie Vinoperfect Anti Dark Spot Serum
4
Best for Dark Spots

Caudalie Caudalie Vinoperfect Anti Dark Spot Serum

If your main skin concern is dark spots, this is the anti-aging serum for you. It contains the patented ingredient Viniferine which was designed to brighten and lighten dark spots while evening out the skin tone.

5
Best for Prevention

Supergoop! Supergoop! SPF 30 Anti-Aging City Sunscreen Serum

Supergoop! SPF 30 Anti-Aging City Sunscreen Serum
5
Best for Prevention

Supergoop! Supergoop! SPF 30 Anti-Aging City Sunscreen Serum

While we love having all of these corrective anti-aging serums at our fingertips, the ultimate secret weapon is sunscreen, which Dr. Engelman also believes. That's why we love this anti-aging sunscreen serum from Supergoop! Its lightweight formula blends in easily for daily wear, even under makeup.

6
Best for Lines and Wrinkles

Elizabeth Arden Elizabeth Arden Prevage Anti-Aging Daily Serum

Elizabeth Arden Prevage Anti-Aging Daily Serum
6
Best for Lines and Wrinkles

Elizabeth Arden Elizabeth Arden Prevage Anti-Aging Daily Serum

This daily serum also comes highly recommended by Dr. Engelmen for its impressive formula that contains cell-strengthening ceramides for renewal and repair. It also contains advanced idebenone technology, which Dr. Engelman notes tops the list of powerful antioxidants for the most protection and repair of your skin.

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7
Best Scent

Image Skincare Image Skincare Vital C Hydrating Anti-Aging Serum

Image Skincare Vital C Hydrating Anti-Aging Serum
7
Best Scent

Image Skincare Image Skincare Vital C Hydrating Anti-Aging Serum

Another longtime favorite of our editorial team, the Vital C anti-aging serum from Image Skincare is one we can't live without. Beyond its creamy consistency and effective formula full of vitamins and antioxidants, it smells like fresh oranges. It'll keep your skin soft and is the perfect pick-me-up for your morning skincare routine. 

8
Best for Large Pores

Dr. Dennis Gross Skincare Dr. Dennis Gross Skincare Alpha Beta Pore Perfecting & Refining Serum

Dr. Dennis Gross Skincare Alpha Beta Pore Perfecting & Refining Serum
8
Best for Large Pores

Dr. Dennis Gross Skincare Dr. Dennis Gross Skincare Alpha Beta Pore Perfecting & Refining Serum

Many of Dr. Dennis Gross' anti-aging products have reached cult status. This one is a customer and editor favorite thanks to its effective formula that contains adipic and salicylic acid, which both help clear blocked pores and minimize their appearance.

9
Best for Hydration

SkinMedica SkinMedica HA5 Rejuvenating Hydrator

SkinMedica HA5 Rejuvenating Hydrator
9
Best for Hydration

SkinMedica SkinMedica HA5 Rejuvenating Hydrator

Hyaluronic acid is a game-changer for any anti-aging routine thanks to its hydrating properties. Dr. Engelman loves this serum for its combination of five different hyaluronic acid molecules to penetrate your skin's various layers. 

Plus, she notes that the Time Release HA, a SkinMedica proprietary ingredient, releases this hydrating ingredient throughout the day for a quenched feel for hours on end.

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10
Best for Brightening

Naturally Serious Illumi-Nation Anti-Fatigue Power Serum

Illumi-Nation Anti-Fatigue Power Serum
10
Best for Brightening

Naturally Serious Illumi-Nation Anti-Fatigue Power Serum

Now 38% Off

Craving that “glass skin” look? The latest anti-aging serum from Naturally Serious will give you that coveted glow. Ingredients like Mediterranean lavender and Persian silk tree help to improve the look of fine lines, wrinkles, and uneven skin tone.

This serum is illuminating and also gives your skin an incredible dewy and youthful look. 

Headshot of Katie McBroom
Katie McBroom
Beauty Editor

Katie McBroom is an award-winning content creator and freelance writer. Prior to contributing to Biography, she served as Content Editor for Google and Beauty Editor for Best Products. Her work has also appeared in publications including CNN, WWD, Business Insider, Forbes, and Men's Health, among others.

Headshot of Jennifer Hussein
Jennifer Hussein
Beauty Editor

Jennifer is the former beauty editor for BestProducts.com, where she’s testing out everything from the latest lip gloss to the craziest skincare trend sweeping the online beauty-verse. Her work has been featured in Allure, Byrdie, HelloGiggles, and more. When she’s not swatching eyeshadow all over her arms, you can find the NYC-based editor scouring for hours on end for vintage finds, eating pad thai, and hanging out with her cat, Chunks.

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